Knowledge Translation (KT) support within Kids Brain Health maximizes the social and economic impacts of the Network’s research and training initiatives.
The KT team supports Kids Brain Health Network, and its funded researchers and trainees using unique and proven approaches that help:
- form and sustain effective partnerships
- translate findings into policy and practice
- engage stakeholders throughout Kids Brain Health activities to maximize impact
Within Networks of Centres of Excellence, the role of Knowledge Translation is seen as generating social and economic benefits for Canadians. Our KT team provided a range of services to support these impacts, including:
- Knowledge Brokering
- Support for KT Events
- KT Products
- KT Capacity Building
- KT Evaluation
- KT Planning
- Stakeholder Engagement
Our Neuroethics Team brought a discerning ethical perspective to Kids Brain Health research, as well as unique contributions to knowledge about issues arising in the diagnosis and treatment of neurodevelopmental disabilities, and family support. Based out of the National Neuroethics Core at the University of British Columbia, and Institute de Recherche Clinique a Montreal, Dr. Judy Illes and Dr. Eric Racine have:
- Explored the impact of life transitions among youth with neurodevelopmental disabilities and their families to understand what supports are needed
- Provided an in-depth understanding of perspectives on safety, risk-benefit trade-offs, receptivity and desirability of stem cell therapy in the CP community
- Created a framework called ouR-HOPE, which aims to improve ethical communication of uncertain neurological prognoses in the neonatal intensive care unit (NICU)
- Developed new tools for informed consent in autism research populations, and pioneered best practices for research participation that are responsive to the communication needs of research participants and their families
- Highlighted the lack of CP and ASD research in First Nations communities, as well as the disproportionate emphasis on Indigenous populations in Canadian FASD studies.
KBHN’s pan-Canadian researchers produce massive amounts of data each year. Our Neuroinformatics Team has collected, managed, and analyzed this valuable material, and created tools that have advanced capacity to cross-compare brain scans with behavioural data and apply insights across different neurodevelopmental disabilities. Their contributions have played a pivotal role in Network research. Highlights include:
- Co-authoring the first paper establishing an epigenetic signature for Fetal Alcohol Spectrum Disorder (FASD), drawing from the largest ever study of children and youth exposed to alcohol before birth;
- Collaborating with the FASD research group on a meta-analysis of publicly available datasets looking at gene expression in animal models of prenatal alcohol exposure (PAE);
- Assisting in the development of the National Cerebral Palsy Registry and Phenocarta, a powerful searchable database that allows researchers to find information about the genes implicated in neurodevelopmental disorders;
- Creating the LORIS database, which standardizes KBHN data (with a specialization in neuroimaging data) to facilitate analysis across the different projects.