Professor, Department of Psychiatry, Faculty of Medicine, University of British Columbia; Canada Research Chair in Neurobiology
Craig is interested in how nerve cells in the brain make synaptic connections and modify connections with experience. She studies these questions of synapse development and synapse plasticity mainly from a cellular and molecular viewpoint. She then uses neuron culture, molecular biology, live cell fluorescence imaging, mouse molecular genetics and electrophysiology to answer these questions.
This fundamental research bears directly on psychiatric disorders. Genetic variants in multiple synaptic organizing complexes are linked to autism spectrum disorders and schizophrenia. She believes that the cellular molecular level studies and animal models will contribute to rational and effective therapies for these disorders.
Projects:
- The ASD Demonstration Project: Neuroimaging and Function
- The ASD Demonstration Project: Next-Generation Genome Sequencing and Identification of Rare DNA Variants
- The ASD Demonstration Project: Clinical Utility Studies
- The ASD Demonstration Project: Identifying Early Behavioural Biomarkers
- The ASD Demonstration Project: Sleep: A Comorbidity Across Disorders
- The ASD Demonstration Project: Translation of Genomic Discoveries into Clinical Practice