PAE

Challenge Fetal alcohol spectrum disorder (FASD), which results from prenatal alcohol exposure, is the most common cause of neurodevelopmental impairments in the western world, with an estimated prevalence of 3-5% in Canada, and as high as 11% in some communities. Diagnosing the disorder is time-consuming and costly — but early diagnosis of children at risk [...]

Challenge Children are usually school-aged by the time they receive a diagnosis for Fetal Alcohol Spectrum Disorder. However, evidence indicates that early intervention is beneficial. Having reliable biomarkers to detect changes related to prenatal alcohol exposure (PAE) could allow clinicians to identify FASD in children at a younger age and therefore provide earlier access to [...]

Challenge Prenatal alcohol exposure is a major cause of behavioural and cognitive deficits in children. Despite extensive research, a unique neurobehavioral profile for children affected by prenatal alcohol exposure has yet to be identified. This research project addressed how genetic and environmental factors interact with prenatal alcohol exposure to produce neurobehavioural and neurobiological deficits in [...]