David Nicholas

The ASD Demonstration Project: Identifying Early Behavioural Biomarkers

2023-10-19T10:49:22-08:00

Challenge Kids in Canada with autism spectrum disorder do not usually receive a diagnosis until the age of four, which is unfortunate given that intervening in early childhood is shown to improve outcomes. Project Summary To help families seize this missed opportunity, researchers involved with the ASD Demonstration Project from KBHN worked to find ASD-related [...]

The ASD Demonstration Project: Sleep: A Comorbidity Across Disorders

2023-10-19T10:52:26-08:00

Challenge Upward of 90 percent of children with neurodevelopmental disabilities (NDDs) have sleep issues, compared to just a quarter of typically developing children. The toll on their well-being—and their families’ quality of life—can be severe. Project Summary In 2013, ASD investigators affiliated with KBHN teamed up to guide the national research agenda on this issue, [...]

The ASD Demonstration Project: Translation of Genomic Discoveries into Clinical Practice

2023-10-19T10:52:46-08:00

Challenge A person’s genome could contain useful information about their risk of autism spectrum disorder, but how should genome sequencing be used in diagnosis, genetic counselling and patient management? What treatments and follow-ups should come after what kinds of test results? And how should these very complex and sometimes ambiguous results be conveyed? How can [...]

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